Table 2.

Sensitivity, specificity, accuracy, and most influential variables (VIP > 1) of the four analyzed OPLS-DA models.

	Group comparison	Sensitivitya	Specificityb	Accuracyc	Most influential variables (VIP value)
Model 1	Control vs. cerebral edema	80%	92.9%	87.5%	RVF (1.21) ΔTVF (1.15) R<t>R (1.14) ΔTVR (1.13) ΔT<t>R (1.05) RVR (1.04)
	Control vs. brain dead	66.7%	90%	77.3%
	Cerebral edema vs. brain dead	76.5%	81.8%	78.6%
Model 2	Cerebral edema vs. brain dead	92.9%	85.7%	89.3%	RNF (1.53) RVF (1.46) ΔTVR (1.26) R<t>R (1.16)
Model 3	Cerebral edema vs. brain dead	86.7%	84.6%	85.7%	RNF (1.24) RVF (1.2) R<t>R (1.19)
Model 4	Cerebral edema vs. brain dead	77.8%	90%	82.1%	RNF (1.54) RVF (1.43)

^aProportion of those with the target condition (brain death, or cerebral edema in case of cerebral edema vs. control) who are correctly classified (true positives) using the optical method measurements.

^bProportion of those without the target condition who are correctly classified (true negatives) using the optical method measurements.

^cAccuracy is the proportion of true results (both true positives and true negatives) of the total number of cases examined.