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. 2018 Mar 25;7(5):2200–2210. doi: 10.1002/cam4.1395

Table 3.

Hazard ratios of total thyroid cancer according to anthropometric features in both sexes

No. cases Person‐years Incidence Crude HR 95%CI P values HR1 95%CI P values HR2 95%CI P values
Men
Height, quintile (cm)
≤160 5 237,452 2.11 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
161–164 5 169,805 2.94 1.39 0.40–4.81 0.601 1.60 0.46–5.58 0.459 1.51 0.43–5.30 0.524
165–168 14 197,846 7.08 3.36 1.21–9.32 0.020 4.23 1.49–12.01 0.007 3.92 1.33–11.55 0.013
≥169 13 181,246 7.17 3.43 1.22–9.63 0.019 4.91 1.67–14.39 0.004 4.24 1.32–13.61 0.015
per 5‐cm increase 1.10 1.04–1.15 <0.001 1.12 1.06–1.17 <0.001 1.12 1.06–1.18 <0.001
Weight, quintile (kg)
≤57 6 204,233 2.94 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
58–63 5 216,350 2.31 0.78 0.24–2.55 0.680 0.84 0.26–2.76 0.773 0.62 0.19–2.06 0.438
64–69 14 175,230 7.99 2.69 1.03–7.00 0.042 3.16 1.20–8.30 0.020 1.82 0.67–4.94 0.237
≥70 12 190,536 6.30 2.13 0.80–5.67 0.131 2.76 1.02–7.50 0.046 1.18 0.40–3.44 0.764
per 5‐kg increase 1.03 1.00–1.07 0.056 1.04 1.01–1.08 0.013 1.01 0.97–1.05 0.733
BMI, quintile (kg/m2)
≤21.51 9 194,240 4.63 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
21.52–23.37 11 193,708 5.68 1.21 0.50–2.93 0.667 1.23 0.51–2.98 0.643 1.20 0.49–2.90 0.688
23.37–25.27 6 201,538 2.98 0.63 0.23–1.78 0.386 0.67 0.24–1.89 0.447 0.62 0.22–1.77 0.375
≥25.28 11 196,862 5.59 1.19 0.49–2.87 0.699 1.33 0.54–3.26 0.529 1.17 0.47–2.90 0.732
per 5‐kg/m2 increase 0.95 0.86–1.06 0.375 0.96 0.87–1.07 0.509 0.95 0.85–1.06 0.364
Women
Height, quintile (cm)
≤148 37 235,738 15.70 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
149–152 43 269,190 15.97 1.02 0.66–1.58 0.938 0.99 0.64–1.54 0.971 0.96 0.61–1.50 0.842
153–156 41 227,575 18.02 1.15 0.74–1.79 0.543 1.12 0.71–1.76 0.636 1.05 0.65–1.68 0.842
≥157 33 176,849 18.66 1.19 0.74–1.90 0.471 1.18 0.72–1.93 0.511 1.07 0.63–1.82 0.794
per 5‐cm increase 1.01 0.98–1.04 0.454 1.01 0.98–1.04 0.513 1.00 0.97–1.04 0.807
Weight, quintile (kg)
≤49 37 245,993 15.04 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
50–53 27 214,117 12.61 0.84 0.51–1.38 0.489 0.82 0.50–1.35 0.435 0.81 0.49–1.34 0.416
54–59 45 237,858 18.92 1.26 0.81–1.95 0.299 1.22 0.79–1.88 0.376 1.21 0.77–1.89 0.416
≥60 45 211,385 21.29 1.42 0.92–2.19 0.116 1.36 0.88–2.11 0.162 1.36 0.85–2.17 0.197
per 5‐kg increase 1.02 1.00–1.04 0.119 1.01 0.99–1.03 0.165 1.01 0.99–1.04 0.218
BMI, quintile (kg/m2)
≤21.23 33 221,944 14.87 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
21.24–23.11 36 228,454 15.76 1.06 0.66–1.70 0.804 1.04 0.65–1.67 0.874 1.03 0.64–1.65 0.911
23.12–25.31 36 230,207 15.64 1.05 0.66–1.69 0.827 1.03 0.64–1.65 0.910 1.02 0.63–1.64 0.935
≥25.32 49 228,747 21.42 1.44 0.93–2.24 0.103 1.43 0.91–2.24 0.120 1.43 0.91–2.24 0.122
per 5‐kg/m2 increase 1.02 0.97–1.07 0.397 1.02 0.97–1.07 0.451 1.02 0.97–1.07 0.459

BMI, body mass index; HR, hazard rate; CI, confidence interval.

HR1: Adjusted for age and public health center area.

HR2: Adjusted for age, public health center area, smoking status, alcohol drinking, leisure‐time physical activity, history of diabetes mellitus, green tea consumption, seaweed consumption, health screening in the previous year, menopausal status (only for women), and age at menarche (only for women). Weight and height were mutually adjusted.