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. 2018 Mar 25;7(5):2200–2210. doi: 10.1002/cam4.1395

Table 4.

Hazard ratios of papillary carcinoma according to anthropometric features in both sexes

No. cases Person‐years Incidence Crude HR 95%CI P values HR1 95%CI P values HR2 95%CI P values
Men
Height, quintile (cm)
≤160 4 237,452 1.68 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
161–164 5 169,805 2.94 1.74 0.47–6.48 0.409 1.97 0.52–7.39 0.317 1.81 0.48–6.90 0.382
165–168 11 197,846 5.56 3.29 1.05–10.33 0.041 3.95 1.23–12.71 0.021 3.63 1.09–12.13 0.036
≥169 11 181,246 6.07 3.62 1.15–11.35 0.028 4.78 1.45–15.76 0.010 4.05 1.12–14.71 0.033
per 5‐cm increase 1.10 1.04–1.16 <0.001 1.12 1.06–1.18 <0.001 1.12 1.05–1.19 <0.001
Weight, quintile (kg)
≤57 6 204,233 2.94 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
58–63 3 216,350 1.39 0.47 0.12–1.87 0.282 0.50 0.12–2.00 0.326 0.36 0.09–1.47 0.156
64–69 12 175,230 6.85 2.31 0.87–6.15 0.094 2.69 1.00–7.23 0.051 1.51 0.54–4.22 0.431
≥70 10 190,536 5.25 1.77 0.64–4.87 0.268 2.28 0.81–6.43 0.117 0.95 0.31–2.90 0.928
per 5‐kg increase 1.03 1.00–1.07 0.089 1.04 1.01–1.08 0.025 1.01 0.96–1.05 0.798
BMI, quintile (kg/m2)
≤21.51 8 194,240 4.12 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
21.52–23.37 8 193,708 4.13 0.99 0.37–2.65 0.990 1.01 0.38–2.71 0.977 0.98 0.37–2.62 0.970
23.37–25.27 5 201,538 2.48 0.60 0.19–1.82 0.363 0.64 0.21–1.96 0.432 0.60 0.19–1.84 0.369
≥25.28 10 196,862 5.08 1.22 0.48–3.09 0.676 1.43 0.56–3.67 0.457 1.26 0.48–3.27 0.637
per 5‐kg/m2 increase 0.94 0.83–1.05 0.269 0.95 0.84–1.07 0.406 0.94 0.83–1.06 0.294
Women
Height, quintile (cm)
≤148 31 235,738 13.15 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
149–152 35 269,190 13.00 0.99 0.61–1.60 0.964 0.94 0.58–1.53 0.794 0.89 0.55–1.46 0.658
153–156 34 227,575 14.94 1.14 0.70–1.85 0.604 1.06 0.64–1.74 0.832 0.97 0.58–1.63 0.912
≥157 29 176,849 16.40 1.25 0.75–2.07 0.388 1.17 0.69–1.99 0.562 1.04 0.59–1.84 0.887
per 5‐cm increase 1.02 0.99–1.05 0.211 1.02 0.98–1.05 0.336 1.01 0.98–1.05 0.581
Weight, quintile (kg)
≤49 30 245,993 12.20 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
50–53 23 214,117 10.74 0.88 0.51–1.52 0.647 0.86 0.50–1.48 0.585 0.84 0.48–1.45 0.523
54–59 37 237,858 15.56 1.27 0.79–2.06 0.323 1.23 0.76–1.99 0.402 1.19 0.72–1.95 0.503
≥60 39 211,385 18.45 1.51 0.94–2.44 0.088 1.46 0.90–2.35 0.122 1.40 0.84–2.33 0.199
per 5‐kg increase 1.02 0.99–1.04 0.144 1.01 0.99–1.04 0.195 1.01 0.99–1.04 0.336
BMI, quintile (kg/m2)
≤21.23 28 221,944 12.62 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
21.24–23.11 31 228,454 13.57 1.08 0.65–1.79 0.780 1.06 0.64–1.78 0.810 1.04 0.62–1.74 0.871
23.12–25.31 30 230,207 13.03 1.03 0.62–1.73 0.904 1.03 0.61–1.72 0.922 1.01 0.60–1.70 0.964
≥25.32 40 228,747 17.49 1.39 0.85–2.25 0.186 1.42 0.87–2.32 0.166 1.40 0.85–2.29 0.183
per 5‐kg/m2 increase 1.01 0.96–1.06 0.608 1.01 0.96–1.07 0.597 1.01 0.96–1.07 0.620

BMI, body mass index; HR, hazard rate; CI, confidence interval.

HR1: Adjusted for age and public health center area.

HR2: Adjusted for age, public health center area, smoking status, alcohol drinking, leisure‐time physical activity, history of diabetes mellitus, green tea consumption, seaweed consumption, health screening in the previous year, menopausal status (only for women), and age at menarche (only for women). Weight and height were mutually adjusted.