Table 4.
No. cases | Person‐years | Incidence | Crude HR | 95%CI | P values | HR1 | 95%CI | P values | HR2 | 95%CI | P values | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Men | ||||||||||||
Height, quintile (cm) | ||||||||||||
≤160 | 4 | 237,452 | 1.68 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
161–164 | 5 | 169,805 | 2.94 | 1.74 | 0.47–6.48 | 0.409 | 1.97 | 0.52–7.39 | 0.317 | 1.81 | 0.48–6.90 | 0.382 |
165–168 | 11 | 197,846 | 5.56 | 3.29 | 1.05–10.33 | 0.041 | 3.95 | 1.23–12.71 | 0.021 | 3.63 | 1.09–12.13 | 0.036 |
≥169 | 11 | 181,246 | 6.07 | 3.62 | 1.15–11.35 | 0.028 | 4.78 | 1.45–15.76 | 0.010 | 4.05 | 1.12–14.71 | 0.033 |
per 5‐cm increase | 1.10 | 1.04–1.16 | <0.001 | 1.12 | 1.06–1.18 | <0.001 | 1.12 | 1.05–1.19 | <0.001 | |||
Weight, quintile (kg) | ||||||||||||
≤57 | 6 | 204,233 | 2.94 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
58–63 | 3 | 216,350 | 1.39 | 0.47 | 0.12–1.87 | 0.282 | 0.50 | 0.12–2.00 | 0.326 | 0.36 | 0.09–1.47 | 0.156 |
64–69 | 12 | 175,230 | 6.85 | 2.31 | 0.87–6.15 | 0.094 | 2.69 | 1.00–7.23 | 0.051 | 1.51 | 0.54–4.22 | 0.431 |
≥70 | 10 | 190,536 | 5.25 | 1.77 | 0.64–4.87 | 0.268 | 2.28 | 0.81–6.43 | 0.117 | 0.95 | 0.31–2.90 | 0.928 |
per 5‐kg increase | 1.03 | 1.00–1.07 | 0.089 | 1.04 | 1.01–1.08 | 0.025 | 1.01 | 0.96–1.05 | 0.798 | |||
BMI, quintile (kg/m2) | ||||||||||||
≤21.51 | 8 | 194,240 | 4.12 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
21.52–23.37 | 8 | 193,708 | 4.13 | 0.99 | 0.37–2.65 | 0.990 | 1.01 | 0.38–2.71 | 0.977 | 0.98 | 0.37–2.62 | 0.970 |
23.37–25.27 | 5 | 201,538 | 2.48 | 0.60 | 0.19–1.82 | 0.363 | 0.64 | 0.21–1.96 | 0.432 | 0.60 | 0.19–1.84 | 0.369 |
≥25.28 | 10 | 196,862 | 5.08 | 1.22 | 0.48–3.09 | 0.676 | 1.43 | 0.56–3.67 | 0.457 | 1.26 | 0.48–3.27 | 0.637 |
per 5‐kg/m2 increase | 0.94 | 0.83–1.05 | 0.269 | 0.95 | 0.84–1.07 | 0.406 | 0.94 | 0.83–1.06 | 0.294 | |||
Women | ||||||||||||
Height, quintile (cm) | ||||||||||||
≤148 | 31 | 235,738 | 13.15 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
149–152 | 35 | 269,190 | 13.00 | 0.99 | 0.61–1.60 | 0.964 | 0.94 | 0.58–1.53 | 0.794 | 0.89 | 0.55–1.46 | 0.658 |
153–156 | 34 | 227,575 | 14.94 | 1.14 | 0.70–1.85 | 0.604 | 1.06 | 0.64–1.74 | 0.832 | 0.97 | 0.58–1.63 | 0.912 |
≥157 | 29 | 176,849 | 16.40 | 1.25 | 0.75–2.07 | 0.388 | 1.17 | 0.69–1.99 | 0.562 | 1.04 | 0.59–1.84 | 0.887 |
per 5‐cm increase | 1.02 | 0.99–1.05 | 0.211 | 1.02 | 0.98–1.05 | 0.336 | 1.01 | 0.98–1.05 | 0.581 | |||
Weight, quintile (kg) | ||||||||||||
≤49 | 30 | 245,993 | 12.20 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
50–53 | 23 | 214,117 | 10.74 | 0.88 | 0.51–1.52 | 0.647 | 0.86 | 0.50–1.48 | 0.585 | 0.84 | 0.48–1.45 | 0.523 |
54–59 | 37 | 237,858 | 15.56 | 1.27 | 0.79–2.06 | 0.323 | 1.23 | 0.76–1.99 | 0.402 | 1.19 | 0.72–1.95 | 0.503 |
≥60 | 39 | 211,385 | 18.45 | 1.51 | 0.94–2.44 | 0.088 | 1.46 | 0.90–2.35 | 0.122 | 1.40 | 0.84–2.33 | 0.199 |
per 5‐kg increase | 1.02 | 0.99–1.04 | 0.144 | 1.01 | 0.99–1.04 | 0.195 | 1.01 | 0.99–1.04 | 0.336 | |||
BMI, quintile (kg/m2) | ||||||||||||
≤21.23 | 28 | 221,944 | 12.62 | 1.00 | (Reference) | 1.00 | (Reference) | 1.00 | (Reference) | |||
21.24–23.11 | 31 | 228,454 | 13.57 | 1.08 | 0.65–1.79 | 0.780 | 1.06 | 0.64–1.78 | 0.810 | 1.04 | 0.62–1.74 | 0.871 |
23.12–25.31 | 30 | 230,207 | 13.03 | 1.03 | 0.62–1.73 | 0.904 | 1.03 | 0.61–1.72 | 0.922 | 1.01 | 0.60–1.70 | 0.964 |
≥25.32 | 40 | 228,747 | 17.49 | 1.39 | 0.85–2.25 | 0.186 | 1.42 | 0.87–2.32 | 0.166 | 1.40 | 0.85–2.29 | 0.183 |
per 5‐kg/m2 increase | 1.01 | 0.96–1.06 | 0.608 | 1.01 | 0.96–1.07 | 0.597 | 1.01 | 0.96–1.07 | 0.620 |
BMI, body mass index; HR, hazard rate; CI, confidence interval.
HR1: Adjusted for age and public health center area.
HR2: Adjusted for age, public health center area, smoking status, alcohol drinking, leisure‐time physical activity, history of diabetes mellitus, green tea consumption, seaweed consumption, health screening in the previous year, menopausal status (only for women), and age at menarche (only for women). Weight and height were mutually adjusted.