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. 2018 May 9;8:7408. doi: 10.1038/s41598-018-25820-y

Figure 5.

Figure 5

Effects of Rivaroxaban on occludin expression and MMP-9 activity in rats. (A) A representative western blot showing changes in occludin expression (n = 6 in each group). Both the Control and Rivaroxaban groups have significantly lower occludin expression level than the Sham group (*P < 0.05), while the Control and Rivaroxaban group have similar occludin expression level (P = 0.28) (one-way ANOVA and a LSD test for post hoc comparisons). (B) A representative zymogram showing changes in MMP-9 activity (n = 6 in each group). Both the Control and Rivaroxaban groups have significantly higher MMP-9 activity than the Sham group (*P < 0.05), while the Control and Rivaroxaban group have similar MMP-9 activity (P = 0.08) (one-way ANOVA and a LSD test for post hoc comparisons).