Table 2.
Breast cancer subtype and marker expression
| Luminal A | Luminal B | HER2 | TNBC | P value | |
|---|---|---|---|---|---|
| Oestrogen receptor α | |||||
| Positive | 74 | 11 | 18 | 0 | — |
| Negative | 0 | 0 | 19 | 17 | |
| Progesterone receptor | |||||
| Positive | 49 | 6 | 10 | 0 | — |
| Negative | 25 | 5 | 27 | 17 | |
| STS | |||||
| Positive | 39 | 4 | 28 | 10 | 0.0274 |
| Negative | 35 | 7 | 8 | 7 | |
| 17βHSD2 | |||||
| Positive | 60 | 9 | 30 | 14 | 0.9934 |
| Negative | 14 | 2 | 6 | 3 | |
| Aromatase | |||||
| Score 1–4 | 20 | 3 | 10 | 7 | 0.69 |
| Score 5–7 | 54 | 8 | 27 | 10 | |
| Oestrogen receptor β1 | |||||
| Average±SD | 183.8 ± 76.8 | 147 ± 74.6 | 164 ± 80.9 | 126.3 ± 85.9 | 0.041 |
| Range | 21.3–300.5 | 75.6–264 | 8.5–313 | 14–264 | |
| Androgen receptor | |||||
| Positive | 62 | 10 | 35 | 10 | 0.0119 |
| Negative | 8 | 1 | 2 | 7 | |
| Glucocorticoid receptor | |||||
| Positive | 40 | 4 | 15 | 9 | 0.2898 |
| Negative | 30 | 7 | 21 | 6 | |
| Ki67 | |||||
| <15% | 25 | 1 | 4 | 1 | <0.001 |
| 15–30% | 24 | 5 | 5 | 3 | |
| >30% | 24 | 5 | 17 | 13 |
Correlation of nuclear receptors and steroidogenic enzymes with breast cancer subtype