Table 4.
Anxiety, depression, and quality of life scores at baseline and 3 months after enrollment (n = 100)
| Variable | Patients without anxiety or depression at baseline (n = 71) |
Patients with anxiety or depression at baseline who did not visit the psycho-oncology clinic (n = 8) |
Patients with anxiety or depression at baseline who did visit psycho-oncology clinic (n = 21) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 3 Months | p value | Baseline | 3 Months | p value | Baseline | 3 Months | p value | |||
| Anxiety or depression | |||||||||||
| HADS-A | 1.30 ± 1.38 | 1.46 ± 2.38 | 0.606 | 4.25 ± 3.06 | 4.25 ± 4.80 | 1.000 | 5.76 ± 3.55 | 4.38 ± 4.23 | 0.258 | ||
| HADS-D | 3.79 ± 1.73 | 5.15 ± 3.99 | 0.009 | 9.13 ± 0.84 | 8.75 ± 5.70 | 0.857 | 8.63 ± 2.01 | 7.14 ± 5.15 | 0.228 | ||
| PHQ-9 | 4.28 ± 2.50 | 5.04 ± 4.52 | 0.217 | 9.00 ± 2.73 | 8.75 ± 6.76 | 0.924 | 11.33 ± 4.61 | 7.24 ± 4.95 | 0.008 | ||
| EORTC QLQ-C30 | |||||||||||
| Global health status | 58.92 ± 17.16 | 60.21 ± 24.04 | 0.713 | 57.29 ± 21.10 | 46.88 ± 22.25 | 0.353 | 41.67 ± 18.63 | 56.35 ± 21.56 | 0.023 | ||
| Function scales | |||||||||||
| Physical | 83.47 ± 14.42 | 81.78 ± 23.23 | 0.603 | 83.33 ± 16.33 | 69.17 ± 28.05 | 0.237 | 73.97 ± 14.28 | 75.24 ± 21.10 | 0.821 | ||
| Role | 85.92 ± 19.24 | 80.75 ± 28.96 | 0.213 | 85.42 ± 13.91 | 66.67 ± 33.33 | 0.164 | 71.43 ± 24.23 | 75.40 ± 27.70 | 0.624 | ||
| Emotional | 83.10 ± 13.58 | 86.50 ± 16.51 | 0.182 | 75.00 ± 19.42 | 69.79 ± 24.37 | 0.644 | 58.73 ± 22.44 | 71.03 ± 24.67 | 0.099 | ||
| Cognitive | 93.90 ± 10.25 | 95.54 ± 7.95 | 0.288 | 89.58 ± 17.68 | 89.58 ± 15.27 | 1.000 | 83.33 ± 17.48 | 86.51 ± 16.35 | 0.547 | ||
| Social | 84.27 ± 20.10 | 78.87 ± 28.31 | 0.192 | 83.33 ± 17.82 | 68.75 ± 30.13 | 0.258 | 65.08 ± 25.77 | 72.22 ± 24.91 | 0.367 | ||
| Symptom scales | |||||||||||
| Fatigue | 25.35 ± 18.42 | 25.19 ± 23.30 | 0.965 | 37.50 ± 27.82 | 47.22 ± 41.47 | 0.591 | 43.92 ± 23.17 | 30.16 ± 20.23 | 0.047 | ||
| Nausea/vomiting | 3.52 ± 8.87 | 5.16 ± 13.68 | 0.397 | 4.17 ± 11.78 | 12.50 ± 11.79 | 0.179 | 14.29 ± 23.74 | 4.76 ± 9.34 | 0.095 | ||
| Pain | 16.20 ± 18.47 | 17.84 ± 25.87 | 0.664 | 10.42 ± 8.63 | 25.00 ± 29.55 | 0.202 | 32.54 ± 27.12 | 20.64 ± 23.51 | 0.136 | ||
| Dyspnea | 8.92 ± 16.86 | 8.45 ± 14.60 | 0.859 | 4.17 ± 11.78 | 12.50 ± 17.25 | 0.278 | 19.05 ± 19.92 | 11.11 ± 19.25 | 0.197 | ||
| Insomnia | 20.66 ± 33.03 | 14.08 ± 26.82 | 0.195 | 8.33 ± 23.57 | 33.33 ± 30.86 | 0.090 | 41.27 ± 40.70 | 34.92 ± 32.45 | 0.579 | ||
| Appetite loss | 25.35 ± 32.10 | 24.41 ± 31.85 | 0.861 | 33.33 ± 39.84 | 37.50 ± 45.21 | 0.848 | 41.27 ± 25.62 | 17.46 ± 27.12 | 0.006 | ||
| Constipation | 21.60 ± 30.39 | 20.19 ± 31.61 | 0.787 | 8.33 ± 15.43 | 29.17 ± 33.04 | 0.128 | 15.87 ± 24.99 | 19.05 ± 35.86 | 0.741 | ||
| Diarrhea | 7.51 ± 17.99 | 7.04 ± 17.74 | 0.876 | 8.33 ± 23.57 | 4.17 ± 11.78 | 0.662 | 11.11 ± 21.94 | 14.28 ± 19.92 | 0.626 | ||
| Financial difficulties | 17.37 ± 25.11 | 22.53 ± 23.08 | 0.204 | 12.50 ± 17.25 | 20.83 ± 24.80 | 0.448 | 39.68 ± 35.93 | 31.74 ± 26.83 | 0.422 | ||
Values are presented as mean ± SD.
HADS-A, Hospital Anxiety and Depression Scale-Anxiety; HADS-D, Hospital Anxiety and Depression Scale-Depression; PHQ-9, Patient Health Questionnaire-9; EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30.