Table 1.
Baseline demographic and laboratory characteristics
| Variable | Control (n = 10) | ASA (n = 10) | CPD (n = 10) | TCG (n = 10) | p value |
|---|---|---|---|---|---|
| Age, yr | 52.0 ± 15.2 | 53.9 ± 12.0 | 66.5 ± 7.3 | 58.3 ± 8.5 | 0.03 |
| Male sex | 5 | 4 | 4 | 7 | 0.40 |
| Height, cm | 155.2 ± 10.2 | 159.2 ± 10.3 | 156.9 ± 6.5 | 175.5 ± 36.6 | 0.17 |
| Body weight, kg | 64.2 ± 13.9 | 58.8 ± 9.1 | 68.7 ± 10.2 | 70.9 ± 9.8 | 0.09 |
| Risk factor | |||||
| Smoking | 3 | 3 | 3 | 4 | 0.25 |
| Alcohol | 3 | 5 | 3 | 3 | 0.21 |
| Hypertension | 5 | 4 | 6 | 7 | 0.26 |
| Diabetes mellitus | 2 | 1 | 2 | 2 | 0.85 |
| Dyslipidemia | 2 | 1 | 2 | 2 | 0.85 |
| White blood cell, /μL | 8,889 ± 2,868 | 7,320 ± 2,150 | 6,368 ± 1,389 | 7,492 ± 1,952 | 0.09 |
| Hemoglobin, g/dL | 13.8 ± 1.1 | 13.9 ± 1.2 | 12.9 ± 2.0 | 14.8 ± 1.3 | 0.06 |
| Platelet, × 1,000/μL | 241.7 ± 75.0 | 271.1 ± 80.9 | 225.0 ± 40.9 | 209.6 ± 34.3 | 0.18 |
| AST, IU/L | 27.0 ± 14.1 | 26.3 ± 9.2 | 33.4 ± 25.1 | 41.8 ± 48.3 | 0.60 |
| ALT, IU/L | 18.3 ± 6.4 | 17.9 ± 6.9 | 31.0 ± 26.2 | 27.9 ± 18.6 | 0.22 |
| Creatinine, mg/dL | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.49 |
| Total cholesterol, mg/dL | 203.2 ± 43.7 | 183.8 ± 35.8 | 161.5 ± 42.9 | 159.4 ± 35.7 | 0.13 |
| LDL-C, mg/dL | 127.1 ± 31.5 | 115.6 ± 17.4 | 109.9 ± 30.0 | 104.7 ± 21.5 | 0.48 |
| HDL-C, mg/dL | 59.0 ± 31.5 | 52.9 ± 13.2 | 47.6 ± 11.6 | 38.3 ± 7.6 | 0.17 |
| Triglyceride, mg/dL | 117.4 ± 84.8 | 168.5 ± 131.6 | 112.1 ± 49.3 | 168.4 ± 111.5 | 0.48 |
| hsCRP, mg/L | 1.1 ± 1.9 | 1.0 ± 1.1 | 1.4 ± 1.7 | 2.2 ± 4.0 | 0.42 |
Values are presented as the mean ± SD.
Control, no anti-platelet agent group; ASA, aspirin group; CPD, clopidogrel group; TCG, ticagrelor group; AST, aspartate transaminase; ALT, alanine transaminase; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; hsCRP, high-sensitive C-reactive protein.