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Body weight change of animals during exposure to carboplatin or hyperoxia in benzo[a]pyrene (B[a]P)-induced lung cancer mouse model. The body weight was measured weekly. Values from the cages per group were averaged for each time point. Significant reduction of body weight by hyperoxia or carboplatin was observed at 28 weeks. CON, control group; CAR, carboplatin group; H, hyperoxia group. ap < 0.05 compared with the CON group. bp < 0.05. cp < 0.05 compared with the B[a]P + CON group.
