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Metabolite clustering and MetPa Analysis of metabolites isolated from lungs of Mtb-infected mice. (A) Two-way hierarchical clustering analysis identified compounds measured by CE-MS and GC-MS of lung samples of Fth+/+ and Fth−/− mice at 9-week postinfection. (B,C) MetPa analysis of metabolic pathways significantly altered in Fth−/− mice infected with Mtb. Statistical testing was performed using the unpaired Student’s t-test.
