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. 2017 Feb 18;23(3):177–186. doi: 10.1093/molehr/gax004

Table I.

Gene set enrichment analysis.

Class Set name FDR
Disease/phenotype Arrest of male meiosis 7.80E-06
Abnormal male meiosis 1.70E-03
Azoospermia 2.50E-03
Decreased testis weight 4.80E-03
Abnormal spermatocyte morphology 5.80E-03
Male infertility 5.90E-03
Small testis 6.80E-03
Male germ-cell apoptosis 7.30E-03
Testicular atrophy 8.10E-03
Abnormal apoptosis 1.70E-02
Abnormal synaptonemal complex 3.90E-02
Gene ontology Mitotic cell cycle (GO:0000278) 1.40E-04
G1/S transition of mitotic cell cycle (GO:0000082) 2.50E-03
DNA repair (GO:0006281) 8.10E-03
Protein K63-linked ubiquitination (GO:0070534) 1.70E-02
GTP catabolic process (GO:0006184) 1.70E-02
Protein K48-linked ubiquitination (GO:0070936) 2.60E-02
Meiosis (GO:0007126) 2.60E-02
G1 phase of mitotic cell cycle (GO:0000080) 4.70E-02
Ubiquitin-dependent protein catabolic process (GO:0006511) 4.80E-02

False discovery rate (FDR) is <0.05. For a list of RNAs associated with different Subclasses, refer to Supplementary Table S2.

Enrichment of specific disease/phenotypes and gene ontologies was performed using GeneSetDB (Araki et al., 2012).