Table I.
Class | Set name | FDR |
---|---|---|
Disease/phenotype | Arrest of male meiosis | 7.80E-06 |
Abnormal male meiosis | 1.70E-03 | |
Azoospermia | 2.50E-03 | |
Decreased testis weight | 4.80E-03 | |
Abnormal spermatocyte morphology | 5.80E-03 | |
Male infertility | 5.90E-03 | |
Small testis | 6.80E-03 | |
Male germ-cell apoptosis | 7.30E-03 | |
Testicular atrophy | 8.10E-03 | |
Abnormal apoptosis | 1.70E-02 | |
Abnormal synaptonemal complex | 3.90E-02 | |
Gene ontology | Mitotic cell cycle (GO:0000278) | 1.40E-04 |
G1/S transition of mitotic cell cycle (GO:0000082) | 2.50E-03 | |
DNA repair (GO:0006281) | 8.10E-03 | |
Protein K63-linked ubiquitination (GO:0070534) | 1.70E-02 | |
GTP catabolic process (GO:0006184) | 1.70E-02 | |
Protein K48-linked ubiquitination (GO:0070936) | 2.60E-02 | |
Meiosis (GO:0007126) | 2.60E-02 | |
G1 phase of mitotic cell cycle (GO:0000080) | 4.70E-02 | |
Ubiquitin-dependent protein catabolic process (GO:0006511) | 4.80E-02 |
False discovery rate (FDR) is <0.05. For a list of RNAs associated with different Subclasses, refer to Supplementary Table S2.
Enrichment of specific disease/phenotypes and gene ontologies was performed using GeneSetDB (Araki et al., 2012).