Table 2.
Brain regions | Brodmann area | Cluster size (voxels) | MNI coordinates (x, y, z) | Peak t value |
---|---|---|---|---|
OCD patients at baseline | ||||
OFC | 11 | 65 | 27, 60, 0 | 6.565 |
Middle frontal gyrus | 138 | 48, 39, 30 | 7.864 | |
Precentral cortex | 6 | 292 | −51, 3, 42 | 7.526 |
White matter | 14,893 | 42, −30, −12 | −39.870 | |
OCD patients at week 12 | ||||
Superior medial frontal gyrus | 112 | 0, 63, 6 | 6.118 | |
Middle frontal gyrus | 6 | 91 | 51, −9, 54 | 6.783 |
Superior temporal gyrus | 48 | 128 | 66, 3, 0 | 10.633 |
Superior temporal gyrus | 22 | 217 | −66, −9, 3 | 9.031 |
Middle cingulate cortex | 88 | 0, 12, 39 | 8.103 | |
White matter | 15,170 | −21, −45, −39 | −45.563 | |
HCs at baseline | ||||
OFC | 11 | 338 | 0, 54, −9 | 6.773 |
Superior temporal gyrus | 38 | 259 | 54, 21, −12 | 7.695 |
Superior temporal gyrus | 38 | 268 | −54, 18, −18 | 7.752 |
Supplementarymotorarea | 6 | 176 | 6, −12, 78 | 8.829 |
White matter | 17,251 | −30, −42, 3 | −39.944 | |
HCs at week 12 | ||||
Superior temporal gyrus | 22 | 103 | −60, −27, 12 | 9.206 |
Superior temporal gyrus | 38 | 179 | 60, 12, −6 | 9.388 |
Superior temporal gyrus | 38 | 99 | −48, 21, −12 | 9.243 |
Inferiortemporalgyrus | 20 | 16,552 | −42, −30, −15 | −33.652 |
Rectus | 11 | 390 | 0, 48, −21 | 7.143 |
Paracentral_Lobule | 4 | 103 | −6, −30, 78 | 6.908 |
MNI, Montreal Neurological Institute; OCD, obsessive‐compulsive disorder; OFC, orbitofrontal cortex.
The threshold was set at a voxel p value <.001, and a cluster p value <.05 (GRF corrected, two‐tailed).