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. 2015 Nov 18;108(3):djv336. doi: 10.1093/jnci/djv336

Table 1.

Algorithms to detect second breast cancer events and cancer recurrences using HMO medical record data, developed by Chubak et al. in the Group Health Cooperative HMO in western Washington state*

Named in this paper Location in Chubak et al. Description Uses SEER variables
Second breast cancer event In main paper
 Algorithm 1† Figure 1 High sensitivity Yes
 Algorithm 2† Figure 2 High specificity, PPV Yes
 Algorithm 3† Figure 3 Extremely high sensitivity Yes
 Algorithm 4 Figure 4 High sensitivity No
 Algorithm 5 Figure 5 High specificity, PPV No
 Algorithm 6 Figure 6 Extremely high sensitivity No
Recurrence-specific In supplementary analysis
 Algorithm 7† Supplementary Figure 2 High sensitivity Yes
 Algorithm 8† Supplementary Figure 3 High specificity Yes
 Algorithm 9† Supplementary Figure 4 High specificity and PPV Yes
 Algorithm 10† Supplementary Figure 5 Extremely high sensitivity Yes
 Algorithm 11 Supplementary Figure 6 High specificity and PPV No
 Algorithm 12 Supplementary Figure 7 Extremely high sensitivity No

* Chubak et al. (5) outlined several approaches to defining second breast cancer events and recurrences using Surveillance, Epidemiology, and End Results (SEER) data and utilization codes. HMO = health maintenance organization; NPV = negative predictive value; PPV = positive predictive value; SEER = Surveillance, Epidemiology, and End Results Program.

† In this paper, we focused on algorithms making use of SEER data, ie, Algorithms 1, 2, 3 and 7, 8, 9, and 10.