Table 3.
Evaluation of Chubak breast cancer algorithms for recurrence in WHI/KPNC data (n = 225) vs published values*
| Algorithm | Published | Kaiser (recurrence) | ||||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | |
| Algorithm 1 | 96 | 95 | 74 | 99 | 86.7 | 89.7 | 56.5 | 97.8 |
| Algorithm 2 | 89 | 99 | 90 | 98 | 76.7 | 92.3 | 60.5 | 96.3 |
| Algorithm 3 | 99 | 81 | 43 | 100 | 83.3 | 81.5 | 41.0 | 97.0 |
| Algorithm 9 | 69 | 99 | 86 | 97 | 63.3 | 95.9 | 70.4 | 94.4 |
| Algorithm 10 | 99 | 81 | 37 | 100 | 76.7 | 85.6 | 45.1 | 96.0 |
* KPNC = Kaiser Permanente Northern California population; NPV = negative predictive value; PPV = positive predictive value; WHI = Women’s Health Initiative Study.