Table 5.
Hazard ratios by prognostic factor using different methods of identifying recurrences*
| Prognostic factor | Method of recurrence identification | |||
|---|---|---|---|---|
|
MR: LACE
HR (95% CI) |
Algorithm 7 (Chubak)
HR (95% CI) |
Algorithm 9 (Chubak)
HR (95% CI) |
Triangulation:
Algorithms 7, 9 and 10% MR HR (95% CI) |
|
| Stage | ||||
| I | Ref | Ref | Ref | Ref |
| II | 1.69 (1.11 to 2.59) | 1.32 (0.83 to 2.10) | 1.61 (0.99 to 2.62) | 1.56 (0.95 to 2.57) |
| IIIa | 4.01 (2.10 to 7.67) | 4.15 (2.01 to 8.57) | 3.77 (1.82 to 7.80) | 4.33 (2.09 to 8.96) |
| Positive nodes | ||||
| 0 | Ref | Ref | Ref | Ref |
| 1–3 | 1.40 (0.93 to 2.12) | 1.19 (0.74 to 1.93) | 1.74 (1.10 to 2.77) | 1.60 (0.99 to 2.58) |
| 4+ | 2.85 (1.81 to 4.51) | 2.27 (1.32 to 3.89) | 3.18 (1.90 to 5.34) | 3.08 (1.81 to 5.23) |
| Alcohol intake | ||||
| ≤0.5g/d | Ref | Ref | Ref | Ref |
| <6g/d | 1.03 (0.74 to 1.44) | 0.99 (0.65 to 1.37) | 1.08 (0.75 to 1.55) | 1.01 (0.69 to 1.47) |
| ≥6g/d | 1.17 (0.84 to 1.64) | 1.02 (0.69 to 1.50) | 1.12 (0.77 to 1.62) | 1.13 (0.77 to 1.64) |
| Physical activity | ||||
| <2.5h/wk | Ref | Ref | Ref | Ref |
| >2.5h/wk | 0.87 (0.64 to 1.16) | 0.70 (0.50 to 0.97) | 0.91 (0.66 to 1.26) | 0.83 (0.60 to 1.16) |
* Models adjusted for age and simultaneously for risk factors. LACE = Life After Cancer Epidemiology cohort; MR = medical record; Ref = referent.