Table 1. Composition of popular cold preservation solutions.
Solutions | EC | UW | HTK (Custodiol) | Custodiol-N | Celsior | LPDG (Perfadex) | Ep4 (EP-TU) | ET-Kyoto | IGL-1 |
---|---|---|---|---|---|---|---|---|---|
K+ | 115 | 125 | 10 | 10 | 15 | 6 | 26 | 44 | 30 |
Na+ | 10 | 25 | 15 | 16 | 100 | 138 | 141 | 100 | 125 |
Cl− | 15 | 20 | 32 | 30 | 71 | 142 | 103 | – | – |
Ca2+ | – | – | 0.015 | 0.02 | 0.25 | – | – | – | 0.03 |
Mg2+ | – | 5 | 4 | 8 | 13 | 0.8 | 4 | 0 | 5 |
Colloid/Impermeant | – | Pentafraction Lactobionate Raffinose | Mannitol | – | Lactobionate Mannitol | Dextran 40 | Dextran 40 | Pentafraction Trehalose | Lactobionate Raffinose Polyethylene glycol |
Buffer | Phosphate Bicarbonate | Phosphate | Histidine | Histidine | Histidine | Phosphate THAM | Phosphate | Phosphate | Phosphate |
Antioxidant | – | Glutathione Allopurinol | Mannitol Tryptophan α-ketoglutarate | Tryptophan α-Ketoglutarate | Glutathione Mannitol | – | – | – | Glutathione Allopurinol |
Glucose | 180 | – | – | – | – | 5 | 10 | – | – |
Amino acids | – | – | Histidine Tryptophan | Histidine N-acetylhistidine Glycine Alanine Tryptophan Arginine Aspartate | Histidine Glutamic acid | – | – | – | – |
Others Sulfate, | – | Sulfate Adenosine | – | Sucrose | – | Sulfate | Sulfate | Nitroglycerin | |
Deferoxamine LK 614 | Dibutyryl cAMP Gluconate | Adenosine | |||||||
Reference | 41 | 41 | 38 | 38 | 41 | 43 | 48 | 49 | 41 |
Note: Values are expressed in mmol/liter unless indicated otherwise.