Table 2.
Compound | R1 | R2 | X | Yield (%) |
---|---|---|---|---|
3i | CH2Ph | iPr | S | 90 |
3j | CH2Ph | Me | S | 89 |
3k | CHPh2 | iPr | S | 88 |
3l | CHPh2 | Me | S | 85 |
3m | 2-(4-morpholino)ethyl | iPr | S | 92 |
3n | 2-(4-morpholino)ethyl | Me | S | 93 |
3o | 2-piperidinoethyl | iPr | S | 95 |
(R)-3o | 2-piperidinoethyl | iPr | S | 90 |
3p | 2-piperidinoethyl | Me | S | 91 |
3r | Bu | iPr | O | 96 |
3s | cHex | iPr | O | 98 |