Table 6.
In vitro antibacterial activity of 3j, 3k, 3l, 3m, 3o, 3p expressed as a minimal inhibitory concentration (MIC) (µg/mL). AMP: ampicillin, NTF: nitrofurantoin, STR: streptomycin.
| Tested Strain |
E. coli NCTC 8196 NCTC 8196 |
S. aureus ATCC 6538 ATCC 6538 |
S. aureus ATCC 29213 ATCC 29213 |
S. epidermidis ATCC 12228 ATCC 12228 |
|---|---|---|---|---|
| Compound | MIC (µg/mL) | |||
| 3j | 256 | 128 | 128 | 128 |
| 3k | 256 | na* | Na | 256 |
| 3l | 256 | 256 | 256 | 256 |
| 3m | na | 128 | 256 | 128 |
| 3o | 64 | 8 | 8 | 4 |
| 3p | 256 | 64 | 64 | 64 |
| NTF | 8 | 16 | 16 | 8 |
| AMP | 4 | 1 | 2 | 1 |
| STR | 1 | 1 | 1 | >512 |
na*—no activity.