Table 1.

Differential Effects on Wound Healing Mediated by DA D₁ versus D₂ Receptors.

	Agonism of D1 Receptors	Agonism of D2 Receptors	Antagonism of D2 Receptors
Wound Closure	Increases [9]	Decreases	Increases [20]
Angiogenesis	Increases [9]	Decreases [11]	Increases [20]
Epidermal hyperplasia	-	Decreases [11]
MSC Mobilization into wound beds			Increases [11]
VEGF-A Expression	Increases [9]	Decreases [25,26]
Cyclic AMP level	Increases [7]	Decreases [11]
Keratinocyte mitosis	Exogenous DA inhibits keratinocyte mitosis in vitro [27]