Table 2.
Cox regression analyses for the 30-day primary endpoint (all-cause death or HF-related rehospitalization)
| 30-day composite endpoint | ||||||
|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||||
| HR | 95%CI | p-value | HR | 95%CI | p-value | |
| Age | 1.03 | 0.99–1.07 | 0.2 | – | – | – |
| Female sex | 1.54 | 0.83–2.87 | 0.2 | 2.28 | 1.19–4.37 | 0.01 |
| NYHA | 1.08 | 0.63–1.87 | 0.8 | |||
| Diabetes | 1.59 | 1.11–2.56 | 0.01 | – | – | – |
| Charlson comorbidity index | 1.28 | 1.14–1.44 | < 0.001 | 1.26 | 1.11–1.43 | < 0.001 |
| Barthel index | 0.99 | 0.98–1.00 | 0.008 | – | – | – |
| Urea | 1.01 | 1.00–1.01 | < 0.05 | – | – | – |
| Creatinine | 0.99 | 0.93–1.06 | 0.7 | |||
| Hb | 0.93 | 0.77–1.11 | 0.4 | |||
| Na | 1.05 | 0.97–1.14 | 0.2 | |||
| NT-proBNPa | 1.63 | 1.21–2.19 | 0.001 | – | – | – |
| ST2a | 1.67 | 1.33–2.11 | < 0.001 | 1.53 | 1.19–1.97 | 0.001 |
| CA125a | 1.12 | 0.83–1.51 | 0.5 | |||
| Hs-TnIa | 1.23 | 0.92–1.63 | 0.2 | |||
aLog-transformed and per 1 SD
CA125 cancer antigen 125, NT-proBNP N-terminal pro-brain natriuretic peptide, hs-TnI high-sensitivity troponin I, ST2 Interleukin-1 receptor-like 1