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. 2018 May 9;18:109. doi: 10.1186/s12877-018-0807-2

Table 4.

Cox regression analyses for 1-year all-cause death

1-year all-cause death
Univariate Multivariate
HR 95%CI p-value HR 95%CI p-value
Age 1.08 1.05–1.11 < 0.001 1.08 1.05–1.12 < 0.001
Female Sex 1.28 0.89–1.85 0.2 1.73 1.16–2.59 0.008
NYHA 2.01 1.40–2.90 < 0.001
Diabetes 1.03 0.83–1.29 0.8
Charlson comorbidity index 1.15 1.05–1.26 0.002 1.17 1.06–1.28 0.001
Barthel index 0.98 0.97–0.99 < 0.001 0.99 0.98–1.00 0.008
Urea 1.01 1.00–1.01 < 0.001
Creatinine 1.00 1.00–1.01 0.4
Hb 0.87 0.77–0.97 0.02
Na 0.97 0.93–1.02 0.2
NT-proBNPa 1.65 1.37–1.98 < 0.001
ST2a 1.86 1.59–2.18 < 0.001 1.45 1.21–1.74 < 0.001
CA125a 1.58 1.33–1.89 < 0.001 1.35 1.11–1.65 0.003
Hs-TnIa 1.29 1.09–1.52 0.003

aLog-transformed and per 1 SD

CA125 cancer antigen 125, NT-proBNP N-terminal pro-brain natriuretic peptide, hs-TnI high-sensitivity troponin I, ST2 Interleukin-1 receptor-like 1