Table 2.
Haematological analyses in the five cats infected with Cytauxzoon sp. Results outside the reference interval are shown in bold font. Cases 1–3 were treated with azithromycin and atovaquone from day 1 to 10 and from day 77 to 86. Case 4 was treated with azithromycin from day 6 to 21 and from day 260 to 270 and with atovaquone from day 11 to 21
| Parameter | Case | Day 0 (presentation) | Week 1 (days 1–7) | Week 2 (days 8–14) | Weeks 4–5 (days 22–35) | Week 10 (days 64–70) | Week 17 (days 113–119) | Week 38 (days 260–266) | Week 122 (days 848–854) |
|---|---|---|---|---|---|---|---|---|---|
| PCV or haematocrit (RI) (%) | 1 | 8a (33–34)c | 22a (33–34)c | 30b (33–34)c | 29b (32–35)c | 34b (34–36)c | 40b (30–37)c | na | 37b (33–45) |
| 2 | 18a (33–34)c | 23a (33–34)c | 33b (33–34)c | 29b (32–35)c | 34b (34–36)c | 38b (30–37)c | na | 36b (33–45) | |
| 3 | 14a (33–34)c | 19a (33–34)c | 25a (33–34)c | 28b (32–35)c | 29b (34–36)c | 36b (30–37)c | na | 32b (33–45) | |
| 4 | 8a (27–47) | 9b (27–47) | 20b (27–47) | 27b (27–47) | na | na | 13b (27–47) | na | |
| 5 | 35b (27-47) | na | na | 41b (27–47) | na | na | na | na | |
| MCV (RI) (fl) | 1 | 71 (47–49)c | na | 41 (47–49)c | na | 34 (42–45)c | na | na | 37 (41–49) |
| 2 | na | na | 51 (47–49)c | na | 38 (42–45)c | na | na | 40 (41–49) | |
| 3 | na | na | 47 (47–49)c | na | 36 (42–45)c | na | na | 41 (41–49) | |
| 4 | na | 36 (37–55) | 61 (37–55) | 47 (37–55) | na | na | 54 (37–55) | na | |
| 5 | na | na | na | 41 (37–55) | na | na | na | na | |
| MCHC (RI) (g/l) | 1 | 330 (291–299)c | na | 350 (291–299)c | na | 360 (308–324)c | na | na | 350 (330–360) |
| 2 | na | na | 320 (291–299)c | na | 350 (308–324)c | na | na | 350 (330–360) | |
| 3 | na | na | 290 (291–299)c | na | 360 (308–324)c | na | na | 360 (330–360) | |
| 4 | na | 392 (263–359) | 317 (263–359) | 336 (263–359) | na | na | 351 (263–359) | na | |
| 5 | na | na | na | 324 (263–359) | na | na | na | na | |
| Reticulocytes (RI) (×109/l) | 1 | 250 (≤ 60)c | na | na | na | na | na | na | na |
| 2 | 570 (≤ 60)c | na | na | na | na | na | na | na | |
| 3 | 470 (≤ 60)c | na | na | na | na | na | na | na | |
| 4 | na | 13 (4–94) | 185 (4–94) | 19 (4–94) | na | na | 163 (4–94) | na | |
| 5 | na | na | na | 20 (4–94) | na | na | na | na | |
| Leucocytes (RI) (×109/l) | 1 | 32 (22–26)c | na | 12 (22–26)c | na | 10 (19–21)c | na | na | 9 (5–13) |
| 2 | na | na | 14 (22–26)c | na | 10 (19–21)c | na | na | 8 (5–13) | |
| 3 | na | na | 12 (22–26)c | na | 8 (19–21)c | na | na | 8 (5–13) | |
| 4 | na | 7 (7–15) | 10 (7–15) | 11 (7–15) | na | na | 8 (7–15) | na | |
| 5 | na | na | na | 10 (7–15) | na | na | na | na | |
| Platelets (RI) (×109/l) | 4 | na | 86 (180–430) | clumps | 407 (180–430) | na | na | clumps | na |
| 5 | na | na | na | clumps | na | na | na | na |
Abbreviations: na not applicable, RI reference interval, PCV packed cell volume, MCV mean corpuscular volume, MCHC mean corpuscular haemoglobin concentration
aValues based on PCV
bValues based on automated haematocrit
cReference intervals for kittens based on [44]; reference intervals change with the age of the kittens