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The signaling relating to cell migration of HSC4. HGF/c-Met signaling increase the filopodia formation, the amount of lamellipodin and the lamellipodia formation. The addition of SU11274, which is a c-Met inhibitor, suppresses the HGF/c-Met signaling and reduces the cell migration of HSC4. On the other hand, EGF/EGFR signaling is not involved in the cell migration of HSC4.
