Table 2.
Correlations among cytokines and chemokines in supernatants
| Cytokines and chemokines | Spearman’s rho [ρ] coefficient | p value (Bonferroni adjusted) |
|---|---|---|
| Pro-inflammatory | ||
| Peripheral blood | ||
| IL-1β and IL-6 | 0.9 | < 0.001 |
| IL-6 and TNF | 0.6 | < 0.001 |
| TNF and IL-1β | 0.5 | < 0.001 |
| IL-6 and IL-8 | 0.3 | < 0.024 |
| Cord blood | ||
| IL-1β and IL-6 | 0.9 | < 0.001 |
| IL-6 and TNF | 0.6 | < 0.001 |
| TNF and IL-1β | 0.5 | < 0.001 |
| Pro-inflammatory and regulatory | ||
| Peripheral blood | ||
| IL-6 and IL-10 | 0.6 | < 0.001 |
| IL-1β and IL-10 | 0.6 | < 0.001 |
| TNF and IL-10 | 0.4 | < 0.001 |
| Cord blood | ||
| Il-6 and IL-10 | 0.6 | < 0.001 |
| IL-1β and IL-10 | 0.6 | < 0.001 |
| TNF and IL-10 | 0.4 | < 0 .001 |
| IL-2 and IL-10 | 0.3 | < 0.015 |
| TH1 | ||
| Peripheral blood | ||
| IL-12 and IL-2 | 0.3 | 0.018 |
| IL-2 and IFN-γ | 0.3 | 0.004 |
| IL-12 and IFN-γ | 0.3 | 0.110 |
| Cord blood | ||
| IL-12 and IL-2 | 0.3 | 0.018 |
| IL-2 and IFN-γ | 0.3 | 0.004 |
| IL-12 and IFN-γ | 0.3 | 0.110 |
| TH2 | ||
| Cord blood | ||
| IL-4 and IL-5 | 0.4 | < 0.001 |
| TH1 and TH2 | ||
| Peripheral blood | ||
| IL-4 and IFN-γ | 0.3 | 0.001 |
| Cord blood | ||
| IL-4 and IFN-γ | 0.5 | < 0.001 |
| IL-4 and IL-12 | 0.3 | < 0.001 |
| IL-4 and IL-2 | 0.3 | < 0.001 |
| TH1 and chemokines | ||
| Peripheral blood | ||
| IL-8 and IFN-γ | − 0.3 | < 0.001 |
| Cord blood | ||
| IL-8 and IL-12 | − 0.3 | 0.011 |
The table shows results that are statistically significant or that are close to significance, after adjustment for multiple comparisons