Table 3.
Neuropsychological test scores for samples of patients diagnosed with posterior cortical atrophy (PCA; n = 18) and early onset Alzheimer’s disease (EOAD; n = 20)
| Neuropsychological tests | PCA | EOAD | P value |
|---|---|---|---|
| MMSE score (30) | 14 (8.8) | 13 (9) | > 1.000a |
| MoCA score (30) | 9.8 (5.7) | 11.3 (5.9) | > 1.000b |
| CDR - SOB (18) | 6 (5.1) | 6.5 (4.5) | > 1.000a |
| Attention & working memory | |||
| Digit span forward (11) | 7 (1.5) | 7 (2) | > 1.000a |
| Digit span backward (9) | 3 (1) | 3 (1) | .898a |
| Executive function | |||
| Trail Making Test A Score (24) | 0 (11) | 17.5 (24) | .087a |
| Trail Making Test B Score (24) | 0 (0) | 0 (10.5) | .794a |
| Language | |||
| Boston naming test (30) | 13.5 (12.8) | 17 (10.5) | .375a |
| Verbal fluency | 9.6 (3.6) | 8.9 (3.3) | > 1.000b |
| Visuo-constructive function | |||
| Rey-Osterreith complex figure copy (36) | 3.5 (4.6) | 17.8 (16.9) | .011a |
| Memory | |||
| AVLT-immediate (45) | 11.6 (5.3) | 11.6 (7.0) | > 1.000b |
| AVLT-delay (15) | 0 (2.3) | 0 (1) | > 1.000a |
| AVLT-clue (15) | 2 (3) | 3 (5.5) | > 1.000a |
| AVLT-recognized (15) | 2.5 (4.3) | 3.5 (5.5) | > 1.000a |
| Calculation (8) | 0.5 (2) | 2 (3.75) | .141a |
| Writing test (21) | 1.5 (15.5) | 21 (6.5) | .002a |
| Reading test (19) | 13.3 (8.2) | 19 (3.5) | .002a |
| Visual-spatial | |||
| Bell cancellation (35) | 7 (10) | 19.5 (22.5) | .018a |
| Overlapping figure (20) | 6.5 (6.3) | 16.5 (5) | .002a |
| Navon figure (12) | 5.5 (7.3) | 12 (2) | .001a |
| Visual-perceptual | |||
| Matching test (10) | 7 (3) | 10 (2.75) | .004a |
| Cookie theft picture (15) | 7.5 (6.5) | 9.5 (4) | .044a |
Data are shown as median (IQR) or mean (SD). Numbers in parentheses next to the test name are maximum possible scores. MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; CDR-SOB, Clinical Dementia Rating-Sum of Box; AVLT, Auditory Verbal Learning Test
aKruskal-Wallis one-way ANOVA followed by post-hoc test
bANOVA followed by Bonferroni test