Table 1.

In vivo Fractional Anisotropy in Rat Brain After Sham Injury, Single or Repeated mTBI.

				p
Region of interest	Sham	mTBI	rmTBI	Sham vs. mTBI	Sham vs. rmTBI	mTBI vs. rmTBI
I Corpus callosum	0.48±0.01	0.45±0.02	0.40±0.01	.036	<.001	<.001
C Corpus callosum	0.47±0.01	0.45±0.04	0.42±0.04	.23	.027	.29
I Cingulum	0.40±0.01	0.39±0.01	0.34±0.02	.56	<.001	<.001
C Cingulum	0.38±0.01	0.41±0.01	0.39±0.04	.12	.50	.31
I Fimbria	0.46±0.02	0.48±0.03	0.49±0.02	.48	.09	.63
C Fimbria	0.48±0.04	0.49±0.02	0.49±0.03	.47	.58	.86
I Internal capsule	0.51±0.03	0.53±0.03	0.52±0.03	.47	.55	.78
C Internal capsule	0.48±0.02	0.50±0.02	0.48±0.04	.20	.97	.34
I Hippocampus	0.19±0.02	0.13±0.02	0.12±0.01	<.001	<.001	.79
C Hippocampus	0.17±0.04	0.14±0.04	0.15±0.03	.52	.23	.63
I Cortex	0.27±0.02	0.25±0.02	0.24±0.01	.15	.005	.37
C Cortex	0.26±0.03	0.25±0.02	0.25±0.02	.53	.24	.64
I External capsule	0.42±0.01	0.40±0.01	0.36±0.01	.034	<.001	<.001
C External capsule	0.39±0.02	0.41±0.02	0.39±0.02	.03	.53	.15
I Amygdala	0.19±0.02	0.20±0.02	0.20±0.03	.70	.72	.96
C Amygdala	0.18±0.03	0.22±0.04	0.18±0.02	.69	.66	.091

Note. I = ipsilateral or impact side; C = contralateral or uninjured side; mTBI = mild traumatic brain injury; rmTBI = repeated mild traumatic brain injury. N for groups are Sham = 6, mTBI = 5, and rmTBI = 8. Results presented as M ± SD. Significant differences are shown in bold.

p < .05 accepted as statistically significant and shown in bold.