Table 4.

In Vivo Mean Diffusivity in Rat Brain After Sham Injury, Single or Repeated mTBI.

				p
Region of interest	Sham	mTBI	rmTBI	Sham vs. mTBI	Sham vs. rmTBI	mTBI vs. rmTBI
I Corpus callosum	0.90±0.02	0.86±0.02	0.86±0.03	.015	.02	.82
C Corpus callosum	0.91±0.03	0.88±0.01	0.89±0.04	.14	.23	.93
I Cingulum	0.83±0.02	0.81±0.03	0.82±0.03	.24	.39	.71
C Cingulum	0.82±0.03	0.80±0.02	0.80±0.03	.26	.13	.70
I Fimbria	0.96±0.02	0.95±0.06	0.94±0.04	.84	.10	.61
C Fimbria	0.96±0.03	0.93±0.03	0.93±0.03	.25	.53	.73
I Internal capsule	0.80±0.02	0.80±0.02	0.80±0.03	.84	.53	.48
C Internal capsule	0.80±0.02	0.79±0.01	0.79±0.02	.29	.11	.50
I Hippocampus	0.83±0.03	0.82±0.01	0.82±0.03	.67	.63	.91
C Hippocampus	0.85±0.03	0.82±0.01	0.82±0.03	.11	.15	.93
I Cortex	0.80±0.02	0.78±0.01	0.79±0.02	.30	.34	.78
C Cortex	0.80±0.03	0.79±0.01	0.79±0.01	.27	.33	.61
I External capsule	0.85±0.02	0.84±0.01	0.84±0.03	.15	.20	.88
C External capsule	0.86±0.03	0.84±0.01	0.84±0.03	.10	.13	.98
I Amygdala	0.91±0.04	0.87±0.03	0.88±0.05	.09	.24	.58
C Amygdala	0.87±0.03	0.88±0.01	0.88±0.03	.72	.68	.90

Note. I = ipsilateral or impact side; C = contralateral or uninjured side; mTBI = mild traumatic brain injury; rmTBI = repeated mild traumatic brain injury. Results presented as M ± SD. N for groups are Sham=6, mTBI=5, and rmTBI=8. Significant differences are shown in bold.

p˂.05 accepted as statistically significant and shown in bold.