Table 5.

Ex Vivo FA Results in Rat Brain After Sham Injury, Single or Repeated mTBI.

				p
Region of interest	Sham	mTBI	rmTBI	Sham vs. mTBI	Sham vs. rmTBI	mTBI vs. rmTBI
I Corpus callosum	0.51±0.03	0.44±0.03	0.40±0.01	<.001	<.001	.033
C Corpus callosum	0.52±0.04	0.50±0.06	0.40±0.01	.52	<.001	.001
I Cingulum	0.40±0.03	0.38±0.01	0.34±0.01	.54	.004	.040
C Cingulum	0.39±0.03	0.41±0.01	0.40±0.02	.32	.74	.37
I Fimbria	0.48±0.03	0.48±0.03	0.49±0.02	.85	.50	.67
C Fimbria	0.48±0.01	0.49±0.03	0.49±0.02	.72	.21	.78
I Internal capsule	0.49±0.04	0.48±0.02	0.46±0.03	.86	.30	.26
C Internal capsule	0.48±0.03	0.49±0.01	0.49±0.02	.76	.54	.65
I Hippocampus	0.19±0.05	0.14±0.01	0.12±0.01	.017	.001	.462
C Hippocampus	0.19±0.06	0.18±0.01	0.16±0.01	.55	.17	.060
I Cortex	0.27±0.02	0.26±0.02	0.23±0.02	.67	.012	.067
C Cortex	0.27±0.01	0.27±0.02	0.27±0.03	.58	.77	.91
I External capsule	0.41±0.02	0.37±0.02	0.33±0.02	.006	<.001	.001
C External capsule	0.42±0.02	0.43±0.04	0.42±0.02	.71	.71	.86
I Amygdala	0.20±0.02	0.20±0.02	0.21±0.02	.72	.69	.47
C Amygdala	0.21±0.02	0.20±0.01	0.20±0.01	.28	.30	.84

Note. I = ipsilateral or impact side; C = contralateral or uninjured side; mTBI = mild traumatic brain injury; rmTBI = repeated mild traumatic brain injury. Results presented as M ± SD. N for groups are Sham=6, mTBI=6, and rmTBI=7. Significant differences are shown in bold.

p<.05 accepted as statistically significant and shown in bold.