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. 2018 May 9;18:110. doi: 10.1186/s12877-018-0796-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Neuromuscular function was decreased in aged rats and GDNF improved the function. a Samples of the CMAPs recorded in the adult group, aged group, aged + NS group and aged + GDNF group. Compared to the adult group, the amplitude was decreased in the aged group (b), the duration, nerve conduction velocity and latency period were increased in the aged group (c, d, e). The treatment of GDNF increased amplitude and decreased the duration, nerve conduction velocity and latency period. Values are shown as mean ± SD (n = 10, **P < 0.01)