Table 3.
Comparison of obese children without liver steatosis (n = 19) and with advanced liver steatosis (n = 42) evaluated in USG according to Saverymuttu et al.
| Parameters | No liver steatosis USG grade 0 median; Q1–Q3 (n = 19) |
Advanced liver steatosis USG grade 2-3 median; Q1–Q3 (n = 42) |
p |
|---|---|---|---|
| Gender, M/F | 12/7 | 36/6 | NS |
| IL-18 (pg/ml) | 279; 198–320 | 335; 249–443 | 0.027 |
| BMI (kg/m2) | 27; 25–30 | 28; 27–33 | NS |
| Waist (cm) | 90; 83–98 | 99; 93–107 | 0.014 |
| ALT (IU/l) | 20; 16–31 | 48; 36–77 | 0.000 |
| AST (IU/l) | 23; 20–29 | 32; 26–45 | 0.000 |
| GGT (IU/l) | 18; 13–23 | 27; 21–35 | 0.000 |
| Bilirubin (mg/dl) | 0.6; 0.5–0.7 | 0.6; 0.4–0.85 | NS |
| Total cholesterol (mg/dl) | 164; 137–182 | 170; 153–191 | NS |
| HDL-C (mg/dl) | 47; 39–56 | 42; 37–50 | NS |
| LDL-C (mg/dl) | 92; 73–111 | 96; 79–121 | NS |
| TG (mg/dl) | 86; 65–116 | 120; 88–167 | 0.004 |
| Glucose (mg/dl) | 90; 83–96 | 95; 90–99 | NS |
| Insulin (μIU/ml) | 14; 8–17 | 17; 12–21 | NS |
| HOMA-IR | 3.2; 1.9–3.7 | 3.9; 3–5.4 | 0.020 |
| Uric acid (mg/dl) | 5.9; 4.8–7 | 6.7; 5.6–7.3 | NS |
| hsCRP (mg/l) | 1.1; 0.7–2.2 | 1.1; 0.5–1.7 | NS |
| Ferritin (ng/ml) | 54; 29–66 | 58; 46–85 | NS |
| A1AT (g/l) | 1.4; 1.2–1.6 | 1.3; 1.2–1.4 | NS |
| 1HMRS (r.u.) | 38; 17–61 | 172; 123–216 | 0.000 |