Table 4.
Comparison of obese children with (n = 72) and without (n = 20) liver steatosis diagnosed with measurement of intrahepatic lipid content using 1HMRS.
| Parameters | No liver steatosis in 1HMRS median; Q1–Q3 (n = 20) |
Liver steatosis in 1HMRS median; Q1–Q3 (n = 72) |
p |
|---|---|---|---|
| Gender, M/F | 12/8 | 58/14 | NS |
| IL-18 (pg/ml) | 275; 205–340 | 342; 249–455 | 0.014 |
| BMI (kg/m2) | 29; 27–32 | 28; 26–32 | NS |
| Waist (cm) | 96; 88–104 | 94; 90–105 | NS |
| ALT (IU/l) | 25; 16–45 | 37; 26–63 | 0.022 |
| AST (IU/l) | 24; 21–33 | 30; 25–39 | 0.013 |
| GGT (IU/l) | 17; 12–23 | 23; 18–31 | 0.016 |
| Bilirubin (mg/dl) | 0.7; 0.5–1.2 | 0.6; 0.4–0.8 | NS |
| Total cholesterol (mg/dl) | 172; 142–182 | 176; 150–192 | NS |
| HDL-C (mg/dl) | 50; 42–52 | 46; 39–55 | NS |
| LDL-C (mg/dl) | 92; 78–114 | 97; 78–121 | NS |
| TG (mg/dl) | 90; 61–120 | 115; 88–164 | 0.008 |
| Glucose (mg/dl) | 90; 85–95 | 92; 85–96 | NS |
| Insulin (μIU/ml) | 14; 8–18 | 15; 12–20 | NS |
| HOMA-IR | 3; 1.9–4 | 3.6; 2.8–4.6 | NS |
| Uric acid (mg/dl) | 5.7; 4.8–7 | 6; 5–6.8 | NS |
| hsCRP (mg/l) | 1; 0.7–2 | 1.3; 0.6–1.9 | NS |
| Ferritin (ng/ml) | 55; 29–73 | 57; 45–86 | NS |
| A1AT (g/l) | 1.4; 1.2–1.6 | 1.3; 1.2–1.5 | NS |
| USG grade of steatosis | 0.5; 0-1 | 1.5; 1-2 | 0.000 |