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. 2018 Apr 26;2018:1874985. doi: 10.1155/2018/1874985

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Copyright © 2018 Chuan Xie et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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H. pylori infection induces gastritis and oxidative damage in the gastric tissue of Balb/c mice. Gastric tissue sections from H. pylori-infected mice were taken after 24 weeks of infection. (a) Pathological changes were evaluated by HE staining. (b) Gastritis histopathology was graded according to the updated Sydney System. (c) Gastric ROS levels were determined by measuring DCF fluorescence. (d) MDA levels in the gastric mucosa were detected. Scale bar = 50 μm; ^∗p < 0.05 and ^∗∗p < 0.01.