Table II.
Anatomical Location of EMD
| EMD at Diagnosis of MM | EMD at Relapse | ||||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Total locations (n) | 19 | Total locations (n) | 92 | ||
| Head and Neck Soft Tissue | 6 | 31.6 | Head and Neck Soft Tissue | 12 | 13.0 |
| Cervical Lymph Node | 2 | 10.5 | Orbit | 3 | 3.3 |
| Scalp | 1 | 5.3 | Scapula | 2 | 2.2 |
| Lip | 1 | 5.3 | Gingiva | 2 | 2.2 |
| Pharynx | 1 | 5.3 | Sinus | 1 | 1.1 |
| Tonsil | 1 | 5.3 | Cranial Nerve | 1 | 1.1 |
| Parotid | 1 | 1.1 | |||
| Larynx | 1 | 1.1 | |||
| Cervical Lymph Node | 1 | 1.1 | |||
| Central Nervous System | 3 | 15.9 | Central Nervous System | 13 | 14.1 |
| Cerebrospinal Fluid | 1 | 5.3 | Dura | 4 | 4.3 |
| Spinal Cord | 1 | 5.3 | Brain | 2 | 2.2 |
| Brain | 1 | 5.3 | Frontal extra-axial mass | 2 | 2.2 |
| Cerebrospinal Fluid | 1 | 1.1 | |||
| Spinal canal | 1 | 1.1 | |||
| Leptomeninges | 1 | 1.1 | |||
| Thecal | 1 | 1.1 | |||
| Subcortical white matter | 1 | 1.1 | |||
| Chest | 4 | 21.1 | Chest | 22 | 23.9 |
| Lung and pleural effusion | 4 | 21.1 | Lung & pleural effusion | 15 | 16.3 |
| Mediastinum | 3 | 3.3 | |||
| Breast | 2 | 2.2 | |||
| Tracheal arch | 1 | 1.1 | |||
| Axillary Lymph Node | 1 | 1.1 | |||
| Abdomen | 5 | 26.3 | Abdomen | 40 | 43.5 |
| Pancreas | 1 | 5.3 | Liver | 14 | 15.1 |
| Peritoneum | 1 | 5.3 | Peritoneal surface | 7 | 7.5 |
| Kidney | 1 | 5.3 | Kidney | 6 | 6.5 |
| Spleen | 1 | 5.3 | Mesentery | 3 | 3.2 |
| Ileum | 1 | 5.3 | Pancreas | 2 | 2.2 |
| Spleen | 2 | 2.2 | |||
| Para-aortic Lymph Node | 1 | 1.1 | |||
| Pelvic Lymph Node | 1 | 1.1 | |||
| Ureter | 1 | 1.1 | |||
| Iliac Lymph Node | 1 | 1.1 | |||
| Buttock | 1 | 1.1 | |||
| Paravertebral | 1 | 1.1 | |||
| Other Soft Tissue | 1 | 5.3 | Other Soft Tissue | 5 | 5.4 |
EMD, extramedullary disease; MM, multiple myeloma