Skip to main content
. Author manuscript; available in PMC: 2018 May 20.
Published in final edited form as: Nat Chem. 2017 Nov 20;10(2):231–236. doi: 10.1038/nchem.2876

Figure 2. Comparison of enediynes produced by wild-type M. chersina and P450 gene deletion strains.

Figure 2

(a) HPLC chromatograms demonstrating loss of 3 production in P450 mutant strains and accumulation of major intermediates 5, 8, and 9 with indicated structures. P450 mutant and wild-type HPLC traces are shown at 540 and 570 nm, respectively. (b) UV-visible spectrum of 3 compared to the UV-visible spectra of 5, 8, and 9.