Table 3.

Odds ratios of cognitive impairment by baseline galectin-3 stratified by diabetes

Diabetes status	Quartile of galectin-3				P for trend∗
	1	2	3	4
	0.1–7.8 ng/mL	7.8–9.9 ng/mL	9.9–12.8 ng/mL	>12.8 ng/mL
No diabetes (293 cases, 411 controls)
Model 2	1 (Ref)	1.22 (0.73–2.05)	2.30 (1.38–3.84)	1.68 (0.95–2.99)	.02
Diabetes (111 cases, 83 controls)
Model 2	1 (Ref)	0.30 (0.06–1.61)	0.23 (0.05–1.14)	0.23 (0.04–1.33)	.10

Abbreviations: LDL, low density lipoprotein; Ref, reference group.

NOTE. Model 2: adjusted for age, sex, race, region, education, income, alcohol use, smoking status, physical activity, hypertension medication use, LDL cholesterol, systolic blood pressure, left ventricular hypertrophy, history of heart disease, atrial fibrillation, congestive heart failure, and estimated glomerular filtration rate.

^∗Trend across quartiles as an ordinal variable 1, 2, 3, and 4.