Table 2.
Changes on the average body weight (g) and the percentage of weight gain of rats subjected to different injections of SDNPs in comparison with rats received normal saline
| Dose | Starting weight | Weight after 20 injections | Weight after 35 injections | Weight after 50 injections | p-value | |||
|---|---|---|---|---|---|---|---|---|
| Control rats (received normal saline) | 230.8±25 | (bw) 257.25±21.5 |
(%) 11.4% |
(bw) 310±24.6 |
(%) 34.3% |
(bw) 335±17.58 |
(%) 45% |
0.027* |
| Treated rats (received SiO2 NPs; 2 mg/kg) | 210.31±31 | (bw) 235.83±29.34 |
(%) 12.1% |
(bw) 272.50±18.55 |
(%) 29.5% |
(bw) 295.17±22.93 |
(%) 30.8% |
0.041* |
Note:
*
A statistically significant difference (p-value of <0.05) using Student’s ANOVA test.
Abbreviations: ANOVA, analysis of variance; NPs, nanoparticles; bw, body weight; SDNPs, silicon dioxide nanoparticles.