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. 2018 Mar 24;2(5):546–560. doi: 10.1002/hep4.1162

Figure 2.

Figure 2

NOX2 modulates HFD‐driven white adipose tissue distribution. Eight‐week‐old WT and NOX2−/− mice were fed an HFD for 22 weeks. (A) Body weight; (B) cumulative weekly food intake; (C) serum leptin level; (D) serum triglyceride level; (E) serum nitrite level; (F) BAT weight and Ucp1 expression; (G) WAT weight; (H) hematoxylin and eosin staining of eWAT; (I) TUNEL staining of eWAT and TUNEL‐positive cell number per field of view. White bars/squares denote WT mice; black bars/squares denote NOX2−/− mice. (A‐I) A representative of two individual experiments, n = 4‐6 mice/condition. Data represent means + SE. Student t test, *P < 0.05, **P < 0.01. Abbreviations: AU, arbitrary unit (relative); TUNEL, terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick‐end labeling.