Table 2.
Pruritus Response to PEBD
| Impact on Pruritus |
FIC1 (n = 21) |
BSEP | ||||
|---|---|---|---|---|---|---|
|
All BSEP (n = 34) |
Common |
Other (n = 9) |
||||
|
D482G (n = 11) |
E297G (n = 14) |
|||||
| No improvement | 4 (19%) | 8 (24%) | 1 (9%) | 3 (21%) | 4 (44%) | |
| Partial improvement | Transient | 4 (19%) | 4 (12%) | 0 (0%) | 2 (14%) | 2 (22%) |
| Sustained | 8 (38%) | 11 (32%) | 4 (36%) | 6 (43%) | 1 (11%) | |
| Complete resolution | Transient | 1 (5%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Sustained | 4 (19%) | 11 (32%) | 6 (55%) | 3 (21%) | 2 (22%) | |
Two patients are excluded from the table: 1 FIC1 patient had complete resolution of pruritus, but the surgery was performed shortly before completion of data collection so it is unknown whether the response was transient or sustained. One other BSEP patient had no information on pruritus response provided.