Table 1.
Clinical and laboratory characteristics of CHB patients and normal controls
| CHB without steatosis N = 27 | CHB with steatosis N = 19 | Normal controls N = 23 | P value | |
|---|---|---|---|---|
|
| ||||
| Mean (SD) | Mean (SD) | Mean (SD) | ||
| Age | 41.7 (13.1) | 47.5 (11.3) | 28.7 (8.6) | <0.001 |
| BMI (kg/m2) | 25.1 (5.7) | 26.4 (3.9) | 22.0 (1.8) | 0.005 |
| FBS (mg/dl) | 90.9 (11.4) | 106.1 (28.9) | 86.9 (9.2) | 0.002 |
| Cholesterol (mg/dl) | 201.9 (46.0) | 206.1 (38.4) | 200.0 (41.5) | NS |
| Triglycerides (mg/dl) | 108.8 (62.6) | 134.9 (45.3) | 68.9 (41.5) | <0.001 |
| HDL-C (mg/dl) | 49.5 (17.2) | 37.5 (9.3) | 60.0 (17.8) | <0.001 |
| LDL-C (mg/dl) | 124.2 (37.5) | 138.1 (34.2) | 121.5 (35.0) | NS |
| VLDL-C (mg/dl) | 21.6 (12.6) | 26.9 (9.0) | 13.9 (8.3) | 0.001 |
| Non-HDL-C (mg/dl) | 152.3 (46.4) | 168.6 (39.6) | 140.0 (41.3) | NS |
| AST (IU/L) | 42.2 (46.9) | 46.4 (34.5) | 21.2 (8.5) | 0.054 |
| ALT (IU/L) | 83.6 (126.3) | 75.4 (43.9) | 42.3 (15.0) | NS |
Abbreviations: BMI, body mass index; FBS, fasting blood sugar; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; VLDL-C, very low density lipoprotein; Non-HDL-C, non-high density lipoprotein cholesterol (total cholesterol minus HDL-C); AST, aspartate transaminase; ALT, alanine transaminase; IL28B, interleukin 28B; SD, standard deviation; NS, not significant.