Table 3.
Genotype frequencies of polymorphisms in HSP90B1 gene between sensitive group and insensitive group and results of HWE
| Polymorphisms (Minor Allele) | Sensitive Group (n=160) | Insensitive Group (n=131) | P-value for HWE | ||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| Wild type | Heterozygous | Homozygous mutants | Wild type | Heterozygous | Homozygous mutants | ||
| rs3794241 (T) | 101 (63.13) | 53 (33.12) | 6 (3.75) | 80 (61.07) | 42 (32.06) | 9 (6.87) | 0.584 |
| rs1165681 (T) | 45 (28.12) | 82 (51.25) | 33 (20.63) | 49 (37.41) | 57 (43.51) | 25 (19.08) | 0.611 |
| rs17034931 (C) | 101 (63.13) | 53 (33.12) | 6 (3.75) | 85 (64.89) | 36 (27.48) | 10 (7.63) | 0.223 |
| rs2722188 (T) | 109 (68.13) | 49 (30.62) | 2 (1.25) | 92 (70.23) | 37 (28.24) | 2 (1.53) | 0.12 |
| rs10778306 (G) | 73 (45.62) | 76 (47.50) | 11 (6.88) | 76 (58.02) | 45 (34.35) | 10 (7.63) | 0.596 |
| rs17034938 (G) | 129 (80.63) | 29 (18.12) | 2 (1.25) | 105 (80.15) | 24 (18.32) | 2 (1.53) | 0.616 |
| rs3794240 (A) | 75 (46.88) | 80 (50.00) | 5 (3.12) | 71 (54.20) | 49 (37.40) | 11 (8.40) | 0.066 |
| rs17034943 (G) | 45 (28.12) | 84 (52.50) | 31 (19.38) | 49 (37.40) | 62 (47.33) | 20 (15.27) | 0.659 |
| rs10861147 (C) | 111 (69.38) | 47 (29.37) | 2 (1.25) | 91 (64.47) | 37 (28.24) | 3 (2.29) | 0.262 |
| rs12426382 (T) | 74 (46.25) | 75 (46.88) | 11 (6.87) | 82 (62.60) | 43 (32.82) | 6 (4.58) | 0.749 |
| rs1165687 (A) | 159 (99.38) | 1 (0.62) | 0 (0) | 130 (99.24) | 1 (0.76) | 0 (0) | 0.953 |
| rs1177457 (T) | 35 (21.88) | 96 (60.00) | 29 (18.12) | 36 (27.48) | 62 (47.33) | 33 (25.19) | 0.138 |