Table 4.
Association of glucocorticoids efficacy and polymorphisms of HSP90B1 gene
SNPs | Dominant Model | Recessive Model | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
|
|
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Crude OR (95% CI) | Crude P-value | Adjusted OR (95% CI) | Adjusted P-value | PBH | Crude OR (95% CI) | Crude P-value | Adjusted OR (95% CI) | Adjusted P-value | PBH | |
rs3794241 | 1.091 (0.678-1.757) | 0.719 | 1.089 (0.664-1.785) | 0.735 | 0.922 | 1.893 (0.656-5.464) | 0.238 | 1.888 (0.641-5.557) | 0.249 | 0.685 |
rs1165681 | 0.655 (0.400-1.073) | 0.093 | 0.872 (0.531-1.432) | 0.142 | 0.389 | 0.908 (0.508-1.622) | 0.744 | 0.927 (0.509-1.689) | 0.804 | 0.966 |
rs17034931 | 0.927 (0.572-1.500) | 0.756 | 0.854 (0.518-1.406) | 0.587 | 0.922 | 2.121 (0.750-6.000) | 0.156 | 1.944 (0.661-5.712) | 0.227 | 0.685 |
rs2722188 | 0.906 (0.549-1.495) | 0.700 | 0.910 (0.543-1.523) | 0.719 | 0.922 | 1.226 (0.170-8.827) | 0.839 | 1.400 (0.179-10.935) | 0.748 | 0.966 |
rs10778306 | 0.607 (0.381-0.968) | 0.036 | 0.640 (0.398-1.031) | 0.067 | 0.380 | 1.120 (0.460-2.725) | 0.803 | 1.065 (0.426-2.660) | 0.893 | 0.966 |
rs17034938 | 1.030 (0.576-1.843) | 0.920 | 1.105 (0.606-2.015) | 0.744 | 0.922 | 1.226 (0.170-8.827) | 0.839 | 1.044 (0.142-7.655) | 0.966 | 0.966 |
rs3794240 | 0.746 (0.469-1.185) | 0.214 | 0.712 (0.442-1.146) | 0.162 | 0.389 | 1.226 (0.170-8.827) | 0.059 | 2.700 (0.890-8.198) | 0.079 | 0.605 |
rs17034943 | 0.655 (0.400-1.073) | 0.093 | 0.647 (0.387-1.079) | 0.095 | 0.380 | 0.750 (0.405-1.389) | 0.360 | 0.783 (0.416-1.474) | 0.449 | 0.706 |
rs10861147 | 0.996 (0.603-1.644) | 0.987 | 1.026 (0.612-1.719) | 0.922 | 0.933 | 1.851 (0.305-11.248) | 0.504 | 2.201 (0.337-14.399) | 0.410 | 0.706 |
rs12426382 | 0.514 (0.321-0.824) | 0.006 | 0.513 (0.317-0.831) | 0.007 | 0.084 | 0.650 (0.234-1.808) | 0.409 | 0.601 (0.211-1.712) | 0.340 | 0.706 |
rs1165687 | 1.225 (0.076-19.770) | 0.886 | 1.177 (0.070-19.834) | 0.910 | 0.922 | - | - | - | - | |
rs1177457 | 0.739 (0.432-1.263) | 0.269 | 0.736 (0.424-1.278) | 0.276 | 0.552 | 1.521 (0.866-2.672) | 0.145 | 1.608 (0.898-2.879) | 0.110 | 0.605 |