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. 2018 Apr 5;7(2):27–39.

Table 4.

Association of glucocorticoids efficacy and polymorphisms of HSP90B1 gene

SNPs Dominant Model Recessive Model


Crude OR (95% CI) Crude P-value Adjusted OR (95% CI) Adjusted P-value PBH Crude OR (95% CI) Crude P-value Adjusted OR (95% CI) Adjusted P-value PBH
rs3794241 1.091 (0.678-1.757) 0.719 1.089 (0.664-1.785) 0.735 0.922 1.893 (0.656-5.464) 0.238 1.888 (0.641-5.557) 0.249 0.685
rs1165681 0.655 (0.400-1.073) 0.093 0.872 (0.531-1.432) 0.142 0.389 0.908 (0.508-1.622) 0.744 0.927 (0.509-1.689) 0.804 0.966
rs17034931 0.927 (0.572-1.500) 0.756 0.854 (0.518-1.406) 0.587 0.922 2.121 (0.750-6.000) 0.156 1.944 (0.661-5.712) 0.227 0.685
rs2722188 0.906 (0.549-1.495) 0.700 0.910 (0.543-1.523) 0.719 0.922 1.226 (0.170-8.827) 0.839 1.400 (0.179-10.935) 0.748 0.966
rs10778306 0.607 (0.381-0.968) 0.036 0.640 (0.398-1.031) 0.067 0.380 1.120 (0.460-2.725) 0.803 1.065 (0.426-2.660) 0.893 0.966
rs17034938 1.030 (0.576-1.843) 0.920 1.105 (0.606-2.015) 0.744 0.922 1.226 (0.170-8.827) 0.839 1.044 (0.142-7.655) 0.966 0.966
rs3794240 0.746 (0.469-1.185) 0.214 0.712 (0.442-1.146) 0.162 0.389 1.226 (0.170-8.827) 0.059 2.700 (0.890-8.198) 0.079 0.605
rs17034943 0.655 (0.400-1.073) 0.093 0.647 (0.387-1.079) 0.095 0.380 0.750 (0.405-1.389) 0.360 0.783 (0.416-1.474) 0.449 0.706
rs10861147 0.996 (0.603-1.644) 0.987 1.026 (0.612-1.719) 0.922 0.933 1.851 (0.305-11.248) 0.504 2.201 (0.337-14.399) 0.410 0.706
rs12426382 0.514 (0.321-0.824) 0.006 0.513 (0.317-0.831) 0.007 0.084 0.650 (0.234-1.808) 0.409 0.601 (0.211-1.712) 0.340 0.706
rs1165687 1.225 (0.076-19.770) 0.886 1.177 (0.070-19.834) 0.910 0.922 - - - -
rs1177457 0.739 (0.432-1.263) 0.269 0.736 (0.424-1.278) 0.276 0.552 1.521 (0.866-2.672) 0.145 1.608 (0.898-2.879) 0.110 0.605