Table 5.
Haplotype analysis for SNPs of HSP90B1 gene and glucocorticoids efficacy
| Haplotypes | Frequency of Insensitive Group | Frequency of Sensitive Group | X2-value | Pearson’s P-value | PBH | OR (95% CI) |
|---|---|---|---|---|---|---|
| CCCGAAAATCCC | 16.31 (0.062) | 24.73 (0.077) | 0.112 | 0.738 | 0.738 | 0.894 (0.464-1.724) |
| CCCGAACATCCC | 30.34 (0.116) | 20.18 (0.063) | 7.491 | 0.006 | 0.048 | 2.273 (1.248-4.139) |
| CCGGAACATCCT | 50.09 (0.191) | 64.39 (0.201) | 0.155 | 0.694 | 0.738 | 1.091 (0.708-1.680) |
| CTGGGAAGTTCC | 22.07 (0.084) | 19.10 (0.060) | 2.430 | 0.119 | 0.317 | 1.664 (0.873-3.171) |
| CTGGGACGTTCC | 10.12 (0.039) | 29.63 (0.093) | 5.032 | 0.025 | 0.100 | 0.436 (0.208-0.916) |
| CTGGGGCATCCC | 11.71 (0.045) | 11.67 (0.036) | 0.631 | 0.427 | 0.584 | 1.401 (0.608-3.226) |
| CTGTAACGCCCT | 21.50 (0.082) | 35.84 (0.112) | 0.600 | 0.438 | 0.584 | 0.798 (0.450-1.414) |
| TCGGAACATCCT | 16.14 (0.062) | 16.05 (0.050) | 0.898 | 0.343 | 0.584 | 1.414 (0.689-2.902) |