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. 2018 Apr 25;8(2):86–99.

Figure 1.

Figure 1

Effect of LPS on plasma and brain levels of IL-1β. A. LPS resulted in an increase in plasma IL-1β levels, which peaked at 2.1 times greater than control levels at 4 h post LPS. Thereafter increased levels of plasma IL-1β decreased only slightly, remaining at 1.8 times greater than control levels at 7-9 d. B. There was more striking increase in IL-1β levels in the brain following LPS, peaking at 7.9 times control levels at 24 h and thereafter decreasing rapidly but remaining approximately 2 times greater than control levels to 7-9 d post LPS. Statistically significant differences noted: mean vs. control (*).