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. 2018 Apr 25;8(2):86–99.

Figure 5.

Figure 5

Effect of LPS on soluble Aβ (1-42) levels in the brain. A. A representative western blot (immunoblot) of whole brain homogenates demonstrates an increase in relative band intensities of soluble Aβ (1-42) 16.5 kD (monomeric) peptide in control rats and in those 24 h following LPS administration. B. Displayed graphically, systemic administration of LPS resulted in increases in soluble Aβ1-42 peptide in whole brain homogenates, peaking at 24 h at 2 times higher than control levels. Beyond 1 d post LPS, soluble Aβ monomeric levels progressively decreased but remained higher than controls for the interval of observation (to 7-9 d). Statistically significant differences noted: (*).