Table 3.
Comparison of plaque density (mean number of plaques per 10X objective field) in various brain regions of control rats and those at various intervals following the intraperitoneal administration of 10 mg/kg LPS
| Effect of LPS on Aβ plaques in the cortex | |||
|---|---|---|---|
|
| |||
| 1 d post LPS | 3 d post LPS | 7-9 d post LPS | |
| N | 8 | 8 | 8 |
| Cortex mean number of plaques/10× field (SE) | 8.96 (1.85) | 14.87 (0.81) | 19.42 (0.61) |
| p vs. control (0) | < 0.01 | < 0.0001 | < 0.0001 |
| p vs. previous time point | < 0.05 | < 0.001 | |
SE = standard error of the mean.