Table 1.

Average level of N-7-(2,3,4-trihydroxybut-1-yl)-guanine (THB-Gua) adducts in the lung of mice exposed to either clean air or 1,3-butadiene ($593\text{ppm}$) for 10 days.

Strain	Treatment	Number of lung samples	$\text{Adducts}/{10}^6$ nucleotides
C57BL/6J	Control (clean air)	5	$0.30\pm 0.18$
	1,3-butadiene	3	$9.60\pm 1.07$*,†
CAST/EiJ	Control (clean air)	4	$0.05\pm 0.12$
	1,3-butadiene	6	$5.09\pm 1.72$*,†

Note: Adduct levels are represented by $\text{average}\pm \text{standard}\text{deviation}$.

^*Indicates a significant difference ($p<0.05$) between the exposed and the control mice of the same strain.

^†Indicates a significant difference ($p<0.05$) between the exposed mice from each strain [based on one-way analysis of variance (ANOVA) with Tukey’s post hoc test].