Fig 5. Effects of PK 11195 and NAC on SDT-induced cytochrome c translocation.
THP-1 macrophages were treated for 3 hours with 5-aminolevulinic acid mediated sonodynamic therapy (ALA-SDT), with or without pretreatment of PK 11195 and NAC. (A) Cytosolic translocation of mitochondrial cytochrome c was examined by western blot of the cytosol and mitochondria. Actin and HSP60 were used as loading controls. (B) Quantitative representation of the Western blot. **P < 0.01, ***P < 0.001 compared to no treatment group, #P < 0.05 compared to ALA-SDT treated group, ##P < 0.01 compared to ALA-SDT treated group.