Table 1. Patient Demographics, HHV8 DNA and Antibody Positivity, and clinical Details for participants with non-KS malignancies.
Pt | Sex | HHV8 Antibody | HHV8 DNA | ART at Time of Sampling | Clinical Diagnosis | Cancer Treatment |
---|---|---|---|---|---|---|
7 | M | - | + | No | NHL | N/A |
8a | F | - | - | No | NHL | R-CODOX-M/IVAC |
9 | M | - | + | Yes | NHL | R-EPOCH |
10 | M | - | + | Yes | NHL | R-CHOP |
11 | M | - | - | Yes | NHL | CHOP, GDP, |
12 | M | - | - | Yes | NHL | R-CHOP, |
13 | M | + | - | No | NHL | R-CHOP |
14 | M | - | - | Yes | NHL | R-CHOP |
15a | M | + | + | Yes | NHL | R-EPOCH, DHAP |
16 | M | + | - | Yes | NHL | R-CHOP, R-ICE |
17 | M | + | - | Yes | NHL | R-EPOCH |
18 | M | - | - | No | NHL | EPOCH, R-ICE |
19 | M | - | - | -b | NHL | R-EPOCH |
20 | M | - | - | Yes | NHL | R-ICE |
21 | M | - | - | Yes | HL | ABVD |
22 | M | - | - | Yes | HL | ABVD |
23 | M | - | - | Yes | AML | Cytarabine-based |
24 | M | - | - | Yes | RCC | carboplatin/gemcitabine |
25 | M | - | - | Yes | HL | Autologous HSCT |
26 | M | + | - | Yes | HL | Allogeneic HSCTc |
27 | M | - | - | Yes | HL | Allogeneic HSCTc |
28 | M | + | - | Yes | HL | Allogeneic HSCTc |
29a | Ma | - | + | Yes | NHL | Allogeneic HSCTc |
Pt = participant; NHL = non-Hodgkin lymphoma; HL = Hodgkin’s Lymphoma; RCC = renal cell carcinoma; AML = acute myeloid leukaemia; R-EPOCH = rituximab, etoposiode, prednisone, vincristine, cyclophosphamide, doxorubicin; R-CODOX-M/IVAC = rituximab, cyclophosphamide, doxorubicin, vincristine, methotrexate/ifosfamide, etoposide, cytarabine; GDP = R-CHOP = rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone; DHAP = dexamethasone, cytarabine, cisplatin; ABVD = doxorubicin, bleomycin, vinblastine, dacarbazine; HSCT = hematopoietic stem cell transplantation;
a longitudinal data on detectable HHV8 levels were available
b Unknown
c Conditioning regimen included busulfan and fludarabine