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. 2018 May 10;13(5):e0194785. doi: 10.1371/journal.pone.0194785

Table 1. Relationship with TaqMeth V of CDO1 and clinicopathological factors at cancer tissue.

Clinicopathological factors Compare items n Average of TaqMeth V P-value
Age 107 --- 0.006 (R2 = 0.070)
Gender Male 65 40.6 ± 22.9 0.73
Female 42 39.1 ± 20.7
Histological type Differentiated type 99 41.3 ± 22.0 0.03
Undifferentiated type 8 24.7 ± 16.4
Tumor location Colon 60 38.7 ± 20.9 0.49
Rectum 47 41.7 ± 23.4
Tumor diameter (cm) 107 --- 0.04 (R2 = 0.038)
Liver metastasis Negative 80 37.2 ± 21.7 0.02
Positive 27 48.6 ± 20.8
Depth of tumor invasion ~sm 13 29.8 ± 20.0 0.07
mp~ 94 41.5 ± 22.0
Lymph node metastasis Negative 60 37.6 ± 21.7 0.19
Positive 47 43.2 ± 22.2
Distant metastasis Negative 88 38.7 ± 21.7 0.16
Positive 19 46.4 ± 22.9
pStage 0 4 25.4 ± 11.7 0.45
I 23 35.6 ± 20.7
II 31 39.2 ± 23.3
III 30 42.2 ± 21.5
IV 19 46.4 ± 22.9
Dukes classification A 27 34.1 ± 23.3 0.30
B 31 39.2 ± 23.3
C 30 42.2 ± 21.5
D 19 46.4 ± 22.9
Dukes classification A and B 58 36.8 ± 21.7 0.10
C and D 49 43.9 ± 21.9
Lymphatic invasion Negative 96 30.2 ± 22.0 0.11
Positive 11 41.2 ± 21.8
Venous invasion Negative 95 32.5 ± 19.4 0.07
Positive 22 42.0 ± 22.3
Infiltrative pattern a 5 24.4 ± 23.2 0.75
b 91 41.7 ± 21.0
c 6 41.2 ± 27.9