Table 1. Summary of NGS results from NIPGS, TE and WB samples obtained from the same blastocyst.
Sample Number | TE biopsy* | NIPGS | WB |
---|---|---|---|
1 | XX; +18 | XX; +18 | XX; +18 |
2 | XX; +20 | XX; +20 | XX; +20 |
3 | XX; -10, +21q21.2–22.3 (21.05Mb) | XX; normal | XX; -10 |
4 | XY; +4, +9q | XY; +4 | XY; +4 |
5 | NA | XX; normal | XX; normal |
6 | XX; +22 | XX; +22 | XX; +22 |
7 | NA | XX; normal | XX; normal |
8 | NA | 68, XXY; -21 | 68, XXY; -21 |
9 | NA | XX; +22 | XX; +22 |
10 | XY; +12 | XY; +5q (70%) | XY; normal |
11 | XX; +22 | XX; normal | XX; normal |
12 | XY; +19 | XY; +19 | XY; +19 |
13 | XX; -22 | XX; -22 | XX; -22 |
14 | XY; -18; -21 | XY; -18; -21 | XY; -18; -21 |
15 | XY; +22 | XY; +22; mosaic -8 (40%) | XY; +22 |
16 | XY; +12q21.1–24.33 (62.08Mb) | XY; +12q21.1–24.33 (62.08Mb) | XY; normal |
17 | XY; +15, +16 | XY; +15, +16 | XY; +15, +16 |
18 | XY; -16 | XY; -16 | XY; -16 |
19 | XX; -16 | XX; -16 | XX; -16 |
20 | XX; +17 | XX; +17 | XX; +17 |
21 | XY; +15 | XY; +15 | XY; +15 |
22 | XY; +11, mosaic -21 (50%) | XY; +11 | XY; +11 |
23 | XY; +19 | XY; +19, mosaic -5 (30%) | XY; +19 |
24 | XX; +16 | XX; +7, +16 | XX; +16 |
25 | XY; -11, +12pter-q14 (64.65Mb) | XY;-11, +12pter-q14 (63.48Mb) | XY;-11, +12pter-q14 (63.48Mb) |
26 | XX; +9, -17 | XX; +9, -17 | XX; +9, -17 |
27 | XY; -4, +22 | XY; -4, +22 | XY; -4, +22 |
28 | XY; -6p 25.3–12.1 (53.69Mb) | XY; -6p 25.3–12.1 (53.69Mb) | XY; -6p 25.3–21`.2 (37.15Mb) |
NA = not available
TE = Trophectoderm
NIPGS = Noninvasive preimplantation genetic screening
WB = Whole blastocyst
* Clinical PGT-A results from TE biopsy perform prior initial embryo vitrification.