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. 2018 May 10;13(5):e0197249. doi: 10.1371/journal.pone.0197249

Fig 2. Root Mean Square Fluctuations (RMSF) of the Cα atoms during the MD simulations of CYP2C9.

Fig 2

The RMSF computed for five merged MD trajectories of (A) WT apo, (B) A477T apo, (C) WT diclofenac-bound, (D) A477T diclofenac-bound, (E) WT losartan-bound and (F) A477T losartan-bound are mapped on the CYP2C9 crystallographic structure (PDB ID: 1OG5) [25]. The color code of RMSF is ranging from 0.7 Å (blue) to 1.6 Å (red). The black arrows show noticeable differences between the WT and the mutant RMSF.